Treatment of chronic manifestations of atopic dermatitis in dogs.
Symptomatic treatment of chronic allergic dermatitis in cats.
Contraindications
Do not use in cases of hypersensitivity to the active substance or any of the excipients.
Do not use in dogs less than six months of age or less than 2 kg in weight.
Do not use in cases with a history of malignant disorders or progressive malignant disorders.
Do not vaccinate with a live vaccine during treatment or within a two-week interval before or after treatment. (See also
Special precautions for use in animals and Interactions).
Do not use in cats infected with FeLV or FIV.
Dosage and method of administration
Dogs: The mean recommended dose of ciclosporin is 5 mg per kg body weight (0.25 ml oral solution per 2.5 kg body weight). The veterinary medicinal product should be given at least 2 hours before or after feeding.
The product should be administered directly into the dog’s mouth on the back of the tongue using the graduated dosing syringe supplied (1 ml oral solution contains 50 mg ciclosporin) and delivering the entire dose.
Cats: The recommended dose of ciclosporin is 7 mg/kg body weight (0.14 ml of oral solution per kg) and should initially be administered daily. The frequency of administration should subsequently be reduced depending on the response. The veterinary medicinal product can be given either mixed with food or directly into the mouth. If given with food, the solution should be mixed with half the normal amount of food consumed using the graduated dosing syringe supplied. (1 ml oral solution contains 50 mg ciclosporin), preferably after a sufficient period of fasting to ensure complete consumption by the cat. When the medicated feed is fully consumed the rest of the food may be given.
Should the cat not accept the product mixed with food, it should be given by inserting the syringe directly into the cat's mouth and delivering the entire dose. If the cat only partially eats the product mixed with food, administration of the product directly into the mouth using the graduated dosing syringe must only be continued the next day.
Duration and frequency of administration
The product will initially be given daily until a satisfactory clinical improvement is seen (assessed by intensity of pruritis and lesion severity - excoriations, miliary dermatitis, eosinophilic plaques and/or self-induced alopecia). This will generally be the case within 4-8 weeks. If no response is obtained within the first 8 weeks, the treatment should be stopped.
Once the clinical signs of atopic/allergic dermatitis are satisfactorily controlled, the preparation can then be given every other day as a maintenance dose. The veterinarian should perform a clinical assessment at regular intervals and adjust the frequency of administration to the clinical response obtained.
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Summary of Product Characteristics (SPC)
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