Treatment of the following conditions caused by bacteria sensitive to doxycycline:
Rhinitis caused by Bordetella bronchiseptica and Pasteurella spp.;
Bronchopneumonia caused by Bordetella spp. and Pasteurella spp.;
Interstitial nephritis caused by Leptospira spp.
Respiratory infections caused by Bordetella bronchiseptica, Chlamydophila felis and Pasteurella spp.
Do not use in cases of hypersensitivity to tetracyclines or to any of the excipients.The product should be administered with caution to animals with dysphagia or diseases accompanied with vomiting, since administration of doxycycline hyclate tablets has been associated with oesophageal erosion.
In order to reduce the likelihood of oesophageal irritation as well as other gastrointestinal side effects, the product should be administered together with food.
Special care should be taken when administering the product to animals with liver disease, since increases in hepatic enzymes have been documented in some animals after doxycycline treatment.
The product should be administered with caution to young animals, since tetracyclines as a class may cause permanent discolouration of the teeth, when administered during tooth development. However, human literature indicates that doxycycline is less likely than other tetracyclines to cause these abnormalities, due to its reduced ability to chelate calcium.
For Oral use.
The recommended dose for dogs and cats is 10 mg doxycycline per kg body weight per day. The majority of routine cases are expected to respond after between 5 and 7 days of therapy. Therapy should continue for 2-3 days beyond the clinical cure for acute infections. In chronic or refractory cases, a longer course of therapy, up to 14 days, may be required. In dogs with interstitial nephritis due to leptospirosis, treatment for 14 days is recommended. In cats with C. felis infections, it is recommended to administer treatment for a minimum period of 28 days in order to ensure elimination of the organism. To ensure a correct dosage body weight should be determined as accurately as possible to avoid underdosing. Tablets should be administered together with food.
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